Alias: Calcium phosphate

Molecular weight: 310.18

Molecular formula: Ca3(PO4)2

Density: 3.14 g/cm3

Melting point: 1670 ° C,

Refractive index: 1.626

CAS No.: 7758-87-4

The β-TCP component is similar to the bone mineral composition and is a white amorphous powder with no odor. Stable in air, decomposed in hot water, soluble in dilute hydrochloric acid and nitric acid, almost insoluble in water, ethanol and acetic acid. Good biological compatibility, degradation under physiological environment, absorption by tissues.

β-tricalcium phosphate (β-TCP) has good biodegradability, biocompatibility and osteoinductive ability. After being implanted into the human body, the degraded calcium and phosphorus can enter the living system and form new bone, so it is widely used. Repair bone tissue. However, its toughness is poor, brittle, and load bearing capacity is poor. Poly L-lactic acid (PLLA) has also been used in bone tissue repair due to its good biocompatibility and biodegradability.

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Main medical uses:

Tricalcium phosphate has good biocompatibility, bioactivity and biodegradability. It is an ideal hard tissue repair and replacement material for human body and has been closely watched in the field of biomedical engineering. A special form of tricalcium phosphate, beta-tricalcium phosphate, is commonly used in medicine. Good biocompatibility, bioactivity and biodegradability. It is an ideal hard tissue repair and replacement material. As a raw material for artificial bone, it has been widely used in orthopedics, plastic surgery and cosmetic surgery, dental surgery, repair due to trauma, Bone defects and bone fusion caused by tumors, inflammation, bone diseases, etc. It can be added to foods as a safe nutritional supplement to enhance calcium intake, and it can also be used to prevent or treat symptoms of calcium deficiency. At the same time, it can also be used as an anti-caking agent, a pH adjuster, a buffering agent, etc. in foods.

β-tricalcium phosphate is mainly composed of calcium and phosphorus, and its composition is similar to the inorganic component of the bone matrix, and is well combined with bone. Animals or human cells can grow, differentiate and multiply on the β-tricalcium phosphate material. Through a large number of experimental studies, it is proved that β-tricalcium phosphate has no adverse reactions to bone marrow hematopoietic function, no rejection reaction, no acute toxicity reaction, no canceration, no allergic phenomenon. Therefore, β-tricalcium phosphate can be widely used in joint and spinal fusion, limb trauma, oral and maxillofacial surgery, cardiovascular surgery, and filling the periodontal cavity. With the deepening of research on β-tricalcium phosphate, its application forms have also diversified, and it has shown good performance in clinical medicine.